EN | FR

Facultatea de Chimie Iaşi

Grup de cercetare_

Ultima actualizare: 25 nov 2016, 13:11:56 (de către Gabriela Pavelescu).

Grupul de cercetare

Compuşi organici cu cicluri penta- şi hexaatomice

 

Coordonator grup

Prof. dr. habil. Mihail-Lucian Bîrsă

 

Contact

Tel: +40 232  201349

Fax: + 40 232 201313

e-mail:E-mail address written as image to avoid SPAM

 

Membri:

1. Prof. dr. Elena Bîcu

2. Prof. dr. habil. Mihai- Lucian Bîrsă

3. Conf. dr. Cătălin- Neculai Lungu

4. Conf. dr. Dalila Belei

5. Lect.dr. Laura Gabriela Sârbu

 

Domenii de cercetare

 

1. Derivati de fenotiazină.

2. Cicloadiţii 3+2 dipolare.

3. "Click chemistry"; Azide si triazoli.

4. Interactiuni intramoleculare in derivati de [2.2]paraciclofan.

5. Flavonoide.

6. Sinteze de catalizatori.

7. Macroheterocicluri de tip coronand; Ciclodextrine naturale.

 

Infrastructura:

 

Spectrometru FTIR Bruker Tensor 27

Spectrofotometru UvVis Varian Carry 100Bio

Reactor fotochimic

Etuve, lampi fotochimice, agitatoare cu incalzire etc.

 

Rezultate semnificative :

 

1.   Bîcu, E.; Birsa, M. L.; Belei, D.; Sarbu, D., Chimie Organică – Exerciţii şi Probleme, Pim, Iaşi, 2003, 246 pp.

2.   Braverman, S.; Cherkinsky, M.; Birsa, M. L., X=C=X, X=O, S, Se, Te, N, P. CO2, COS, CS2, Isocyanates, Isothiocyanates, Carbodiimides, Se, Te, P Analogs in Science of Synthesis, Houben-Weyl Methods of Molecular Transformations, Georg Thieme Verlag, Stuttgart, Vol. 18.2; 2005, pp 55-310.

3.     Birsa, M. L., Carbanions and Electrophilic Aliphatic Substitution in Organic Reaction Mechanisms 2003, 2005-2012, Knipe, A. C. Ed., John Wiley and Sons, Chichester.

4.    Birsa, M. L., Elimination Reactions in Organic Reaction Mechanisms 2004-2012, Knipe, A. C. Ed., John Wiley & Sons, Chichester.

5.    Belei, D., Bicu, E., Jones, P. G., Birsa, M. L.,” A New Synthetic Methodology for the Pyrrolidine Ring”, Synlett, (2010), 931-933.

6.   Belei, D., Bicu, E., Jones, P. G., Birsa, M. L.,” A Selective Synthesis of Enamines vs. Aziridines”, J. Heterocycl. Chem., (2011) 48, 129-134.

7.     Birsa, M. L., Jones, P. G., Hopf, H. ”[2.2]Paracyclophanes with New Bridges”, Synfacts, 2011, 387.

8.   Belei, D., Abuhaie, C., Bicu, E., Jones, P. G., Hopf, H., Birsa, M. L., “A Direct Synthesis of Octahydropyrrolo[2,1,5-cd]indolizin-6-one Derivatives”, Synlett, 2012, 545.

9.  Hopf, H., Jones, P. G.,^Nicolescu, A., Bicu, E., *Birsa, M. L*.*, Belei, D., "A facile synthesis of Pechmann dyes", /Chem. Eur. J/., *20*, 5565-5568 (2014).

10. Sarbu, L. G., Hopf, H., Jones, P. G., *Birsa, M. L.**, "Selenium halide-induced bridge formation in [2.2]paracyclophanes" /Beilstein J.Org. Chem./, *10*, 2550-2555 (2014).

11. Sarbu, L. G., Bahrin, L. G., Jones, P. G., *Birsa, M. L.*, Hopf, H., "[2.2]Paracyclophane derivatives containing tetrathiafulvalene moieties <https://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-11-207&vt=f&tpn=0&bpn=searchResult>", /Beilstein J. Org. Chem./, *11*, 1917-1921 (2015).

12. Bahrin, L. G., Sarbu, L. G., Hopf, H., Jones, P. G., Babii, C., Stefan, M., *Birsa, M. L.**, "The influence of halogen substituents on the biological properties of sulfur-containing flavonoids", /Bioorg. Med.Chem./, *24*, 3166-3173 (2016).

12. Gosav, S., Paduraru, N., Maftei, D.,*Birsa, M. L.*, Praisler, M., "Quantum chemical study of a derivative of 3-substituted dithiocarbamic flavanone", /Spectrochimica Acta A://Molecular and Biomolecular Spectroscopy/, *172*, 115-125 (2017).